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Adipogen rabbit anti asc al177 polyclonal antibody
Rabbit Anti Asc Al177 Polyclonal Antibody, supplied by Adipogen, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/antibody+asc+polyclonal+rabbit+to/pmc12484792-377-34-39
Average 86 stars, based on 1 article reviews
rabbit anti asc al177 polyclonal antibody - by Bioz Stars, 2026-10
86/100 stars

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Related Articles

Western Blot:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Virus:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Recombinant:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Adjuvant:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Isolation:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Amplex Red Cholesterol Assay:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Retroviral:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Plasmid Preparation:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Software:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).

Incubation:

Article Title: The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.
Article Snippet: Inflammation is a tightly regulated response of the innate immune system to infection and tissue injury and aims to restore tissue homeostasis.. Several soluble cytokines have crucial roles in this process, including various inflammatory interleukins that lack a signal peptide, such as interleukin 1β (IL-1β) or IL-18 (ref. 1).. Both of those cytokines are synthesized as inactive precursors and require posttranslational processing by active caspase-1 for the generation of their mature active forms1.

Article Title: Instructions for Flow Cytometric Detection of ASC Specks as a Readout of Inflammasome Activation in Human Blood
Article Snippet: The following Antibodies (Abs) were used: rabbit polyclonal anti-ASC (AL177, Adipogen, San Diego, CA, USA), anti-rabbit-IgG-AlexaFluor488 (Invitrogen, Waltham, MA, USA), and lineage-specific antibodies CD3 PerCP, CD4 APC, CD14 APC-Cy7, CD16 PE-Cy7 (Biolegend, San Diego, CA, USA).

Article Title: Oxysterol restraint of cholesterol synthesis prevents AIM2 inflammasome activation
Article Snippet: Western blots were performed with rabbit polyconal anti-caspase-1 p10 (M-20, Santa Cruz), mouse monoclonal anti-NLRP3 (Cryo-2, Adipogen), rabbit polyclonal anti-ASC (AL177, Adipogen), and goat anti-IL-1β (polyclonal; R&D).

Article Title: Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.
Article Snippet: After permeabilization, cells was stained with rabbit plyclonal anti-ASC (AL177, AdipoGen, diluted 1:200) followed by AlexaFluor 568 goat anti-rabbit IgG (Invitrogen, diluted 1:1000).



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Adipogen rabbit anti asc al177 polyclonal antibody
Rabbit Anti Asc Al177 Polyclonal Antibody, supplied by Adipogen, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/antibody+asc+polyclonal+rabbit+to/pmc12484792-377-34-39
Average 86 stars, based on 1 article reviews
rabbit anti asc al177 polyclonal antibody - by Bioz Stars, 2026-10
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Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
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Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Polyclonal Rabbit Anti Mouse Asc Antibody Al177, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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polyclonal rabbit anti-mouse asc antibody al177 - by Bioz Stars, 2026-10
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Adipogen rabbit-polyclonal anti-asc al177
Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Rabbit Polyclonal Anti Asc Al177, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/asc+antibody/pm39256305-186-5-8
Average 90 stars, based on 1 article reviews
rabbit-polyclonal anti-asc al177 - by Bioz Stars, 2026-10
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Adipogen rabbit anti-human asc polyclonal antibody al177
Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Rabbit Anti Human Asc Polyclonal Antibody Al177, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/asc+antibody/pm38838044-155-17-23
Average 90 stars, based on 1 article reviews
rabbit anti-human asc polyclonal antibody al177 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Adipogen rabbit polyclonal anti-asc al177
Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Rabbit Polyclonal Anti Asc Al177, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/asc+antibody/pm38065956-307-6-10
Average 90 stars, based on 1 article reviews
rabbit polyclonal anti-asc al177 - by Bioz Stars, 2026-10
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Adipogen rabbit anti-asc rabbit polyclonal pab al177
Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Rabbit Anti Asc Rabbit Polyclonal Pab Al177, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/asc+antibody/pm37945612-272-6-14
Average 90 stars, based on 1 article reviews
rabbit anti-asc rabbit polyclonal pab al177 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Adipogen rabbit anti-asc rabbit polyclonal pab al177, 1:200 dilution
Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Rabbit Anti Asc Rabbit Polyclonal Pab Al177, 1:200 Dilution, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/rabbit+polyclonal+anti-asc+(al177)/asc+antibody/pmc10636019-255-6-14
Average 90 stars, based on 1 article reviews
rabbit anti-asc rabbit polyclonal pab al177, 1:200 dilution - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

90
Adipogen anti-asc (al177), rabbit polyclonal ab
Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, <t>AL177</t> staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males
Anti Asc (Al177), Rabbit Polyclonal Ab, supplied by Adipogen, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti-asc (al177), rabbit polyclonal ab - by Bioz Stars, 2026-10
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Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, AL177 staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males

Journal: Journal of Neuroinflammation

Article Title: Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer’s disease associated with inflammasome activation and ASC speck propagation

doi: 10.1186/s12974-025-03501-8

Figure Lengend Snippet: Ethanol activates NLRP3 inflammasome in the hippocampus of APP/PS1 mice. Representative image and quantification of NLRP3 ( A ), ASC ( B ), and caspase-1 ( C ) protein levels in the hippocampal tissue lysates from WT and APP/PS1 mice analyzed by Western blot. Mean ± SEM. N = 8–12. D Caspase-1 activity measured in the hippocampal tissue lysates using a fluorescent assay, displayed as a fold change in the fluorescence compared to WT-water group. E IL-1β protein levels in the hippocampus of WT and APP/PS1 mice evaluated by ELISA. Mean ± SEM. N = 8–14. F Quantification of ASC fluorescence staining in the hippocampus. Mean ± SEM. N = 8–10. Two-way ANOVA with Tukey’s post hoc test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. G Representative pictures of ASC staining (red) localized around and inside Aβ plaques (green, 6E10 staining) in the hippocampus of water- and ethanol-treated APP/PS1 mice. Scale bar – 50 µm. H Representative pictures of ASC (red, AL177 staining) co-localization with microglia (IBA1, green). DAPI-blue. Scale bar – 20 µm. I Representative pictures of ASC (red, AL177 staining) co-localization with astrocytes (GFAP, light blue). DAPI-blue. Scale bar – 20 µm. ● denotes females, ○ denotes males

Article Snippet: Rabbit polyclonal anti-ASC (AL177) , Adipogen , AG-25B-0006-C100.

Techniques: Western Blot, Activity Assay, Fluorescence, Enzyme-linked Immunosorbent Assay, Staining